hrp0095p1-256 | Diabetes and Insulin | ESPE2022

Analysis of NGS panel examination in patients suspected of MODY in a single tertiary hospital

Joo Eunyoung , Park Jisun , Kim Sujin , Lee Ji-Eun

Introduction: Maturity-onset diabetes of the young (MODY) is a genetically heterogeneous group of monogenic endocrine disorders which is inherited as autosomal dominant pattern and characterized pancreatic β-cell dysfunction. It has been estimated to represent around 1% to 6% of all diabetes. The hallmark of MODY is that the onset is before 25 years of age and inherited in an autosomal dominant manner. Generally, there are several known genes that cause M...